3- (1- (Dimethylamino) ethyl] phenol
![3- (1- (Dimethylamino) ethyl] phenol egosipụtara onyonyo](http://cdn.globalso.com/jindunchem-med/image271.png)
3- (1- (Dimethylamino) ethyl] phenol
A na-eji 3- (1- (Dimethylamino) ethyl] phenol dị ka etiti nke Rivastigmine tartrate.
Rivastigmine tartrate bụ rivastigmine ọrịa Alzheimer ọgwụ, rivastigmine bụ physostigmine derivative site Novartis maka oge mbụ nke ọma mepụtara ahia aha Exelon (exelon), a molekul na e nwere carbamate Ọdịdị, bụ ụdị amino acid nke cholinesterase inhibitor na-ahọrọ, nwekwara ike igbochi. na acetylcholinesterase na butyrylcholinesterase, cholinergic neurons site na-egbu oge ntọhapụ nke acetylcholine mmebi na ume na-akwalite cholinergic akwara conduction, nwere ike melite cognition ọrụ ọrịa ogbugbo site cholinergic, si otú imeziwanye cognitive ọrụ nke ọrịa Alzheimer.Njikọ protein Rivastigmine plasma adịghị ike, dị mfe site na mgbochi ụbụrụ ọbara, nke nwere oke nhọrọ ụbụrụ.Ọ bụghị naanị na ọ na-ahọrọ nke ọma na cortex cerebral cortex na hippocampus na-emetụta nke ọma, kamakwa ọ na-egbochikwa subtype nke AChE na ụbụrụ ụbụrụ, na-ebute mbelata arụmọrụ nke mmetụta cholinergic peripheral.Rivastigmine in vivo ọkara ndụ dị mkpụmkpụ na ogologo oge nke ime ihe.N'adịghị ka tacrine, ngwaahịa a na hippocampus na cortex nke mmetụta inhibitory enzyme G1 siri ike karị.A na-enyo enyo na ụlọ ọgwụ maka ọgwụgwọ ụdị mgbaka Alzheimer dị nro ma na-agafeghị oke, ma ọ bụ ọrịa Alzheimer nwere ike iche na ọ bụ ọrịa Alzheimer n'ụlọ ọgwụ.
JIN DUN Medical nwereNtozu ISO ma mezuo ụkpụrụ mmepụta GMP, n'ọrụ ụlọ na mba ọzọ ọgwụ synthesis ọkachamara na ọgaranya ahụmahụ na-eduzi ụlọ ọrụ R&D.
TECHNOL OGY URU
● Nnukwu nrụgide catalytic Hydrogenation.Mmeghachi omume Hydrogenolysis nrụgide dị elu.Mmeghachi omume Cryogenic (<-78%C)
●Aromatic Heterocyclic Synthesis
●Mmeghachi omume
● Mkpebi Chiral
●Heck, Suzuki,Negishi,Sonogashira .Mmeghachi omume Gignard
Akụrụngwa
Ụlọ nyocha anyị nwere ngwaọrụ nnwale na nnwale dị iche iche, dị ka: NMR (Bruker 400M), HPLC, Chiral-HPLC, LC-MS, LC-MS/MS (API 4000) , IR, UV, GC, GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Iche Iche Nyocha Calorimeter (DSC), Electron Microscope...
Otu R&D
Jindun Medical nwere otu ndị ọrụ R&D ọkachamara, ma were ọtụtụ ndị ọkachamara n'ime ụlọ na ndị mba ofesi na-eduzi R&D, na-eme ka njikọ anyị dịkwuo mma na nke ọma.
Anyị enyerela aka ọtụtụ ụlọ ọrụ na-emepụta ọgwụ ụlọ, dịkaHansoh, Hengrui na HEC Pharm.N'ebe a, anyị ga-egosi akụkụ nke ha.
Usoro nhazi nke mbụ:
Nọmba ekwentị: 110351-94-5
Nhazi nke abụọ:
Nọmba ekwentị: 144848-24-8
Usoro nke atọ:
Nọmba cas: 200636-54-0
1.Hazie ndị etiti ọhụrụ ma ọ bụ API.Otu dị ka nkesa nke dị n'elu, ndị ahịa nwere ihe achọrọ maka Intermediates ma ọ bụ API, na ha enweghị ike ịchọta ngwaahịa ndị dị mkpa na ahịa, mgbe ahụ anyị nwere ike inye aka hazie.
2.Usoro nkwalite maka ngwaahịa ochie.Ndị otu anyị ga-enyere aka ịkwalite ma melite mmepụta dị otú ahụ nke ụzọ mmeghachi omume ya mere ochie, ọnụ ahịa mmepụta dị elu, na arụmọrụ dị ala.Anyị nwere ike ịnye akwụkwọ zuru oke maka ịnyefe teknụzụ na nkwalite usoro, nyere ndị ahịa aka maka mmepụta nke ọma.
Site na ebumnuche ọgwụ ruo IND, JIN DUN Medical na-enye gịngwọta R&D ahaziri otu nkwụsị.
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![pentamethylene bis [1- (3,4-dimethoxybenzyl) -3,4-dihydro-6,7-dimethoxy-1H-isoquinoline-2-propionate], dioxalate](http://cdn.globalso.com/jindunchem-med/28.png)
