4-chloro-n- (4,5-dihydro-1h-imidazol-2-yl) -6-methoxy-2-methyl-5-pyrimidinamin;
4-chloro-n- (4,5-dihydro-1h-imidazol-2-yl) -6-methoxy-2-methyl-5-pyrimidinamin;
Ọ na-arụ ọrụ site na-akpali akpali Central presynaptic alpha 2-receptors.Mmetụta hypotensive ya yiri nke nifedipine, onye na-emegide calcium, na captopril, onye na-egbochi ACE.Maka ọbara mgbali elu dị mkpa.
Ngwaahịa a kwesịrị ịnakwere ụkpụrụ nke ọgwụ onwe onye.N'ozuzu, na-amalite site na obere doses, ya bụ, 0.2mg, otu ugboro n'ụbọchị, were n'ụtụtụ.Ekwesịrị ime mgbanwe usoro onunu ogwu na etiti izu atọ ruo mgbe enwetara nsonaazụ na-eju afọ.Usoro a na-emekarị bụ 0.2mg otu ugboro, ugboro abụọ n'ụbọchị (ututu na mgbede).Oke kachasị kwa oge agaghị agafe 0.4mg, yana oke kwa ụbọchị agaghị agafe 0.6mg.Maka ndị ọrịa nwere ụkọ akụrụ dị nro ma ọ bụ agafeghị oke, otu dose ekwesịghị gafere 0.2 mg ma ọ bụ kwa ụbọchị ekwesịghị gafere 0.4 mg.
Ngwaahịa a bụ agonist α2-anabata, nke bụ ọgwụ antihypertensive imidazoline.A na-eji ya maka ọbara mgbali elu nke mbụ na nke abụọ.
N'ihi na ọ na-egbochi nzuzo na mmegharị nke eriri afọ eriri afọ, ọ dịkwa mma maka ndị ọrịa nwere ọbara mgbali elu na-arịa ọrịa ọnya.Nchikota nke ọgwụ a na diuretics nwere ike ime ka ọ dịkwuo mma.Ọ bụ ọgwụ antihypertensive etiti dị ike yana ọgwụ mgbochi hypertensive nke abụọ.A na-enye ya na mpaghara na ophthalmology.Ngwaahịa a nwere mmetụta nke ibelata nrụgide intraocular, ọ dịghị emetụta nwa akwụkwọ na usoro mmezi anya.Ọ nwere ike igbochi arịa ọbara na anya, belata mmepụta nke ọchị ọchị, ma nweta mmetụta nke ibelata nrụgide intraocular.Ọ na-amalite ịrụ ọrụ 15 nkeji mgbe anya dara ma nwee ike ịnọgide na-enwe mmetụta maka ihe dịka awa 8.
Ọkọlọtọ:EP10
Isi ihe nyocha:97.5-102.0%
Mputa:Na-acha ọcha ma ọ bụ fọrọ nke nta ka mgbe ntụ ntụ
ngwugwu:1kg / akpa ma ọ bụ dị ka ndị ahịa chọrọ
JIN DUN Medical nwereNtozu ISO ma mezuo ụkpụrụ mmepụta GMP, n'ọrụ ụlọ na mba ọzọ ọgwụ synthesis ọkachamara na ọgaranya ahụmahụ na-eduzi ụlọ ọrụ R&D.
TECHNOL OGY URU
● Nnukwu nrụgide catalytic Hydrogenation.Mmeghachi omume Hydrogenolysis nrụgide dị elu.Mmeghachi omume Cryogenic (<-78%C)
●Aromatic Heterocyclic Synthesis
●Mmeghachi omume
● Mkpebi Chiral
●Heck, Suzuki,Negishi,Sonogashira .Mmeghachi omume Gignard
Akụrụngwa
Ụlọ nyocha anyị nwere ngwaọrụ nnwale na nnwale dị iche iche, dị ka: NMR (Bruker 400M), HPLC, Chiral-HPLC, LC-MS, LC-MS/MS (API 4000) , IR, UV, GC, GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Iche Iche Nyocha Calorimeter (DSC), Electron Microscope...
Otu R&D
Jindun Medical nwere otu ndị ọrụ R&D ọkachamara, ma were ọtụtụ ndị ọkachamara n'ime ụlọ na ndị mba ofesi na-eduzi R&D, na-eme ka njikọ anyị dịkwuo mma na nke ọma.
Anyị enyerela aka ọtụtụ ụlọ ọrụ na-emepụta ọgwụ ụlọ, dịkaHansoh, Hengrui na HEC Pharm.N'ebe a, anyị ga-egosi akụkụ nke ha.
Usoro nhazi nke mbụ:
Nọmba ekwentị: 110351-94-5
Nhazi nke abụọ:
Nọmba ekwentị: 144848-24-8
Usoro nke atọ:
Nọmba cas: 200636-54-0
1.Hazie ndị etiti ọhụrụ ma ọ bụ API.Otu dị ka nkesa nke dị n'elu, ndị ahịa nwere ihe achọrọ maka Intermediates ma ọ bụ API, na ha enweghị ike ịchọta ngwaahịa ndị dị mkpa na ahịa, mgbe ahụ anyị nwere ike inye aka hazie.
2.Usoro nkwalite maka ngwaahịa ochie.Ndị otu anyị ga-enyere aka ịkwalite ma melite mmepụta dị otú ahụ nke ụzọ mmeghachi omume ya mere ochie, ọnụ ahịa mmepụta dị elu, na arụmọrụ dị ala.Anyị nwere ike ịnye akwụkwọ zuru oke maka ịnyefe teknụzụ na nkwalite usoro, nyere ndị ahịa aka maka mmepụta nke ọma.
Site na ebumnuche ọgwụ ruo IND, JIN DUN Medical na-enye gịngwọta R&D ahaziri otu nkwụsị.
JIN DUN Medical na-ekwusi ike ịmepụta otu ndị nwere nrọ, na-emepụta ngwaahịa ndị nwere nsọpụrụ, ndị na-akpachapụ anya, siri ike, na-eme ka ọ bụrụ onye mmekọ tụkwasịrị obi na enyi ndị ahịa!
