4-Methoxybenzylalkohol;ANISALKOHOL;4-methoxy-benzenemethano;

Nke etiti maka Moxonidine
Nwere ike kpalie ndị na-anabata α2 etiti ma mee ka mmetụta antihypertensive dị ka clonidine.Ọnụọgụ nnabata ọnụ (90%) na bioavailability (88%) dị elu, na enweghị mmetụta ngafe mbụ.Ọnụ ọgụgụ kachasị elu nke ọbara na-apụta 1 ruo 3 awa mgbe ịṅụchara ọgwụ ahụ.Akọrọ na-ewepụta ọtụtụ n'ime ya.t1/2 dị ihe dị ka awa 2.A na-eji ụlọ ọgwụ maka ọbara mgbali elu.

Mmiri mmiri na-enweghị agba ma ọ bụ ntakịrị odo.Ebe mgbaze bụ 23-25.5 Celsius C, ebe a na-esi esi bụ 159 ° C, njupụta nke ikwu bụ 1.113 (15/15 ° C), na ntinye ntụgharị bụ 1.5442.Ọ dị mfe soluble na mmanya na ether, ọ fọrọ nke nta ka ọ ghara ịsọpụrụ na mmiri.

Ngwaahịa a nwere ísì ụtọ fennel dị ụtọ ma na-ejikarị akwadebe jasmine, lilac na ihe ụtọ ndị ọzọ, ọ dịkwa mma maka nkwadebe ihe nsure ọkụ.Ngwaahịa a bụ ngwa nri nke GB2760-86 nke obodo m nyere ikike.A na-ejikarị ya akwadebe ụtọ dị ka vanilla, chocolate, koko, almond, na peach.A na-ejikwa ya na njikọ organic na dịka ihe mgbaze.

Site na mbelata nke anisaldehyde.Cannizzaro na-emeghachi omume na anise, formaldehyde na sodium hydroxide na ethanol iji mepụta mmanya p-methoxybenzyl.

Mgbe enwetara ethanol site na distillation, a na-ewepụta oyi akwa mmanụ enwetara site na mmeghachi omume na benzene, acidified site na ịgbakwunye acetic acid, wee wepụ ya na sodium bicarbonate ka ọ bụrụ alkaline na-adịghị ike.Mgbe ịsachara mmiri na nnọpụiche, a na-enweta benzene site na distillation, a na-edobekwa ihe fọdụrụ na oghere iji nweta p-methoxy Benzyl mmanya.

Ọ na-arụ ọrụ site na-akpali akpali Central presynaptic α2-receptors.Mmetụta antihypertensive ya yiri nke calcium antagonist nifedipine na ACE inhibitor captopril.Eji maka ọbara mgbali elu dị mkpa.