Guanosin

A na-eji Guanosin dị ka etiti Valaciclovir.
Valacyclovir bụ ọgwụ analọgụ guanine.A na-eji ya na ọgwụgwọ ọrịa herpes simplex na ọrịa herpes zoster na ọrịa ndị a na-ebute site ná mmekọahụ.Ngwaahịa a bụ precursor nke acyclovir.A na-etinye ya ngwa ngwa mgbe nchịkwa ọnụ gasịrị ma gbanwee ngwa ngwa n'ime acyclovir n'ime ahụ.A na-akpọ mmetụta antiviral site na acyclovir.Mgbe acyclovir abanyela na mkpụrụ ndụ nje herpes, ọ na-asọmpi na deoxynucleoside maka nje thymidine deoxynucleoside kinase ma ọ bụ cell kinase, na ọgwụ na-phosphorylated n'ime activated acyclic guanosine triphosphate.Dị ka mkpụrụ nke mmegharị nje, acyclovir na-asọmpi deoxyguanine triphosphate maka nje DNA polymerase, nke na-egbochi njikọ DNA nje ma gosipụta mmetụta antiviral.Ọrụ antiviral nke ngwaahịa a na vivo dị mma karịa acyclovir, na ntinye ọgwụgwọ nke ụdị nje virus herpes simplex I na ụdị II bụ 42.91% na 30.13% dị elu karịa acyclovir n'otu n'otu.Ọ nwekwara mmetụta ọgwụgwọ dị elu na nje varicella zoster.