Hydroxypyrazolodpyrimidine pyrazolo (3,4-d) pyrimidin-1-ol
Hydroxypyrazolodpyrimidine pyrazolo (3,4-d) pyrimidin-1-ol
A na-eji ya n'ụlọ ọgwụ na hyperuricemia nke mbụ na nke abụọ, karịsịa na ndị ọrịa nwere hyperuricemia, yana ndị ọrịa na-arịa ọrịa akụrụ, yana ndị ọrịa nwere gout ugboro ugboro ma ọ bụ na-adịghị ala ala, yana ndị ọrịa nwere hyperuricemia.A na-eji ya na ndị ọrịa nwere Gouty nephropathy iji belata mgbaàmà ma belata nguzobe nke uric acid uric acid.nkume gout;eji na uric acid akụrụ nkume na uric acid akụrụ ọrịa.
Ngwaahịa a na metabolites ya nwere ike igbochi xanthine oxidase, nke mere na hypoxanthine na xanthine enweghị ike ịtụgharị n'ime uric acid, ya bụ, njikọ nke uric acid na-ebelata, si otú a na-ebelata mkpokọta uric acid n'ime ọbara ma belata mkpokọta urate. ọkpụkpụ, nkwonkwo na akụrụ, ọgwụ ndị nwere ike igbochi njikọ nke uric acid.Ngwaahịa a nwere ike igbochi ọrụ nke enzymes ọgwụ imeju.
(1) .A na-ejikwa hyperuricemia nke mbụ na nke abụọ, karịsịa ndị na-emepụta oke uric acid, maka hyperuricemia nwere ụkọ akụrụ;
(2) .N'ihi na ọgwụgwọ nke gout, adabara ugboro ugboro ma ọ bụ na-adịghị ala ala gout.Maka ndị ọrịa nwere nephropathy gouty, ọ nwere ike belata mgbaàmà ma belata nguzobe nke uric acid n'ime akụrụ;
(3) .Tophi;
(4) .Ejiri ya maka nkume akụrụ uric acid na (ma ọ bụ) uric acid nephropathy.
Ọkọlọtọ:usp42
Nyocha:98-102%
Mputa:Na-acha ọcha ma ọ bụ ọ fọrọ nke nta ka ọ bụrụ ntụ ntụ
ngwugwu:25kg / akpa
Enwere mbelata ụmị ọkpụkpụ, nke nwere ike ịkpata pancytopenia, a ga-akwụsịkwa ọgwụ ahụ ma ọ bụrụ na ọ dị mkpa.Na-aṅụ mmiri buru ibu n'oge ọgwụ, ma mee ka mmamịrị na-anọpụ iche ma ọ bụ alkaline wepụ diuretic acid.A ghaghị itinye ngwaahịa a mgbe nnukwu mbufụt nke gouty ogbu na nkwonkwo kwụsịrị (na-emekarị ihe dị ka izu abụọ ka mmalite).N'oge ọgwụ, a na-enyocha foto ọbara na imeju na akụrụ mgbe niile.
JIN DUN Medical nwereNtozu ISO ma mezuo ụkpụrụ mmepụta GMP, n'ọrụ ụlọ na mba ọzọ ọgwụ synthesis ọkachamara na ọgaranya ahụmahụ na-eduzi ụlọ ọrụ R&D.
TECHNOL OGY URU
● Nnukwu nrụgide catalytic Hydrogenation.Mmeghachi omume Hydrogenolysis nrụgide dị elu.Mmeghachi omume Cryogenic (<-78%C)
●Aromatic Heterocyclic Synthesis
●Mmeghachi omume
● Mkpebi Chiral
●Heck, Suzuki,Negishi,Sonogashira .Mmeghachi omume Gignard
Akụrụngwa
Ụlọ nyocha anyị nwere ngwaọrụ nnwale na nnwale dị iche iche, dị ka: NMR (Bruker 400M), HPLC, Chiral-HPLC, LC-MS, LC-MS/MS (API 4000) , IR, UV, GC, GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Iche Iche Nyocha Calorimeter (DSC), Electron Microscope...
Otu R&D
Jindun Medical nwere otu ndị ọrụ R&D ọkachamara, ma were ọtụtụ ndị ọkachamara n'ime ụlọ na ndị mba ofesi na-eduzi R&D, na-eme ka njikọ anyị dịkwuo mma na nke ọma.
Anyị enyerela aka ọtụtụ ụlọ ọrụ na-emepụta ọgwụ ụlọ, dịkaHansoh, Hengrui na HEC Pharm.N'ebe a, anyị ga-egosi akụkụ nke ha.
Usoro nhazi nke mbụ:
Nọmba ekwentị: 110351-94-5
Nhazi nke abụọ:
Nọmba ekwentị: 144848-24-8
Usoro nke atọ:
Nọmba cas: 200636-54-0
1.Hazie ndị etiti ọhụrụ ma ọ bụ API.Otu dị ka nkesa nke dị n'elu, ndị ahịa nwere ihe achọrọ maka Intermediates ma ọ bụ API, na ha enweghị ike ịchọta ngwaahịa ndị dị mkpa na ahịa, mgbe ahụ anyị nwere ike inye aka hazie.
2.Usoro nkwalite maka ngwaahịa ochie.Ndị otu anyị ga-enyere aka ịkwalite ma melite mmepụta dị otú ahụ nke ụzọ mmeghachi omume ya mere ochie, ọnụ ahịa mmepụta dị elu, na arụmọrụ dị ala.Anyị nwere ike ịnye akwụkwọ zuru oke maka ịnyefe teknụzụ na nkwalite usoro, nyere ndị ahịa aka maka mmepụta nke ọma.
Site na ebumnuche ọgwụ ruo IND, JIN DUN Medical na-enye gịngwọta R&D ahaziri otu nkwụsị.
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