A na-eji L-Valine mee ihe dị ka etiti nke Valaciclovir.
Valacyclovir bụ ọgwụ analọgụ guanine.A na-eji ya na ọgwụgwọ ọgwụgwọ ọrịa herpes simplex na ọrịa herpes zoster na ọrịa ndị a na-ebute site ná mmekọahụ.Ngwaahịa a bụ ihe mmalite nke acyclovir.A na-etinye ya ngwa ngwa mgbe nchịkwa ọnụ gasịrị ma gbanwee ngwa ngwa n'ime acyclovir n'ime ahụ.A na-akpọ acyclovir mmetụta antiviral.Mgbe acyclovir abanyela na mkpụrụ ndụ nje herpes, ọ na-asọmpi na deoxynucleoside maka nje thymidine deoxynucleoside kinase ma ọ bụ cell kinase, na ọgwụ na-phosphorylated n'ime activated acyclic guanosine triphosphate.Dị ka mkpụrụ nke mmegharị nje, acyclovir na-asọmpi deoxyguanine triphosphate maka nje DNA polymerase, nke na-egbochi njikọ DNA nje ma gosipụta mmetụta antiviral.Ọrụ antiviral nke ngwaahịa a na vivo dị mma karịa acyclovir, na ntinye ọgwụgwọ nke ụdị nje virus herpes simplex I na ụdị II bụ 42.91% na 30.13% dị elu karịa acyclovir n'otu n'otu.Ọ nwekwara mmetụta ọgwụgwọ dị elu na nje varicella zoster.
JIN DUN Medical nwereNtozu ISO ma mezuo ụkpụrụ mmepụta GMP, n'ọrụ ụlọ na mba ọzọ ọgwụ synthesis ọkachamara na ọgaranya ahụmahụ na-eduzi ụlọ ọrụ R&D.
TECHNOL OGY URU
● Nnukwu nrụgide catalytic Hydrogenation.Mmeghachi omume Hydrogenolysis nrụgide dị elu.Mmeghachi omume Cryogenic (<-78%C)
●Aromatic Heterocyclic Synthesis
●Mmeghachi omume
● Mkpebi Chiral
●Heck, Suzuki,Negishi,Sonogashira .Mmeghachi omume Gignard
Akụrụngwa
Ụlọ nyocha anyị nwere ngwaọrụ nnwale na nnwale dị iche iche, dị ka: NMR (Bruker 400M), HPLC, Chiral-HPLC, LC-MS, LC-MS/MS (API 4000) , IR, UV, GC, GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Iche Iche Nyocha Calorimeter (DSC), Electron Microscope...
Otu R&D
Jindun Medical nwere otu ndị ọrụ R&D ọkachamara, ma were ọtụtụ ndị ọkachamara n'ime ụlọ na ndị mba ofesi na-eduzi R&D, na-eme ka njikọ anyị dịkwuo mma na nke ọma.
Anyị enyerela aka ọtụtụ ụlọ ọrụ na-emepụta ọgwụ ụlọ, dịkaHansoh, Hengrui na HEC Pharm.N'ebe a, anyị ga-egosi akụkụ nke ha.
Usoro nhazi nke mbụ:
Nọmba ekwentị: 110351-94-5
Nhazi nke abụọ:
Nọmba ekwentị: 144848-24-8
Usoro nke atọ:
Nọmba cas: 200636-54-0
1.Hazie ndị etiti ọhụrụ ma ọ bụ API.Otu dị ka nkesa nke dị n'elu, ndị ahịa nwere ihe achọrọ maka Intermediates ma ọ bụ API, na ha enweghị ike ịchọta ngwaahịa ndị dị mkpa na ahịa, mgbe ahụ anyị nwere ike inye aka hazie.
2.Usoro nkwalite maka ngwaahịa ochie.Ndị otu anyị ga-enyere aka ịkwalite ma melite mmepụta dị otú ahụ nke ụzọ mmeghachi omume ya mere ochie, ọnụ ahịa mmepụta dị elu, na arụmọrụ dị ala.Anyị nwere ike ịnye akwụkwọ zuru oke maka ịnyefe teknụzụ na nkwalite usoro, nyere ndị ahịa aka maka mmepụta nke ọma.
Site na ebumnuche ọgwụ ruo IND, JIN DUN Medical na-enye gịngwọta R&D ahaziri otu nkwụsị.
JIN DUN Medical na-ekwusi ike ịmepụta otu ndị nwere nrọ, na-emepụta ngwaahịa ndị nwere nsọpụrụ, ndị na-akpachapụ anya, siri ike, na-eme ka ọ bụrụ onye mmekọ tụkwasịrị obi na enyi ndị ahịa!