pentamethylene bis [1- (3,4-dimethoxybenzyl) -3,4-dihydro-6,7-dimethoxy-1H-isoquinoline-2-propionate], dioxalate

pentamethylene bis [1- (3,4-dimethoxybenzyl) -3,4-dihydro-6,7-dimethoxy-1H-isoquinoline-2-propionate], a na-eji dioxalate dị ka etiti nke Cisatracurium besylate.
Cisatracurium besylate bụ ụdị nnu benzene sulfonate nke atracurium.Ọ bụ ụdị ihe na-eme ka ahụ ike na-eme ihe na-adịghị emebi emebi na ọrụ ya dị ka tubocurarine.Ọ nwere oge mmalite nke 1 nkeji na oge nke 15 nkeji.Usoro ọgwụgwọ anaghị emetụta ọrụ obi, imeju na akụrụ.O nweghikwa ihe nchikota.Ọ nwekwara ike ịkpalite ntọhapụ nke histamine mgbe ejiri ya na nnukwu doses.Maka izu ike nke anụ ahụ ma ọ bụ njikwa iku ume chọrọ n'ịwa ahụ, ma e jiri ya tụnyere ọgwụ anestetiiki bụ isi akwara na-eme ka ahụ dị jụụ, cisatracurium besylate adịghị metabolized site na imeju ma ọ bụ akụrụ, ma nwee nkwụsi ike nke obi;Mmetụta ya nke ntụrụndụ anụ ahụ bụ ugboro 3 siri ike dị ka atracurium na-enweghị mmetụta ọ bụla nke obi.A na-etinyekarị Cisatracurium besylate na nhụsianya izugbe, a pụkwara iji ya mee ihe na intubation, na-agwọ ọrịa imeju na akụrụ, nke a na-eji na ịwa ahụ obi na ndị agadi na ndị ọrịa ụmụaka.
E jiri ya tụnyere atracurium, ngwaahịa a enweghị mmetụta ọjọọ na-adabere na dose nke ntọhapụ histamine;Otú ọ dị, mwepu bụ na ndị ọrịa nwere imeju na akụrụ adịghị arụ ọrụ kwesịrị iji nlezianya mee ihe.
Ebe ọ bụ na 1996 maka oge mbụ mgbe ọgwụ a batara n'ahịa na UK, mba mba ọzọ ejirila nwayọọ nwayọọ tinye ya iji dochie vecuronium na atracurium dị ka isi ihe na-eme ka ahụ ike na-ahụ maka ahụike.