6-tetra-O-actyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl] oxy] phenyl]
![6-tetra-O-actyl-1-C-[4-chloro-3-[[4-[[[(3S)]-tetrahydrofu-ran-3-yl]oxy] phenyl] egosipụtara](http://cdn.globalso.com/jindunchem-med/0ecf55f0.jpg)
6-tetra-O-actyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl] oxy] phenyl]
Ngwaahịa a bụ mbadamba ihe mkpuchi na-acha odo odo na-acha odo odo, na-acha ọcha ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ na-acha ọcha mgbe ọ wepụsịrị mkpuchi ahụ.
Ngosipụta
Ngwaahịa a dabara adaba maka ọgwụgwọ ụdị ọrịa shuga 2.
monotherapy
A na-eji ngwaahịa a yana njikwa nri yana mmega ahụ iji melite njikwa shuga ọbara na ndị ọrịa nwere ụdị ọrịa shuga 2.
A na-ejikarị metformin hydrochloride mee ihe
Mgbe naanị metformin hydrochloride enweghị ike ịchịkwa shuga ọbara nke ọma, enwere ike iji ngwaahịa a yana metformin hydrochloride iji meziwanye njikwa shuga ọbara na ndị ọrịa nwere ụdị ọrịa shuga 2 dabere na nri na mmega ahụ.
A na-ejikarị metformin hydrochloride na sulfonylureas mee ihe.
Mgbe ijikọ metformin hydrochloride na sulfonylureas enweghị ike ịchịkwa shuga ọbara nke ọma, enwere ike iji ngwaahịa a yana metformin hydrochloride na sulfonylureas iji meziwanye njikwa shuga ọbara nke ndị ọrịa nwere ụdị ọrịa shuga 2 na-adabere na nri na mmega ahụ.
Mgbochi ọgwụ
A naghị atụ aro ngwaahịa a maka ndị ọrịa nwere ụdị ọrịa shuga 1 ma ọ bụ maka ọgwụgwọ ketoacidosis mamịrị.
Nkọwapụta
(1) 10 mg;(2) 25 mg.
Usoro onunu ogwu
Usoro akwadoro.
Usoro akwadoro nke ngwaahịa a bụ 10 mg n'ụtụtụ, otu ugboro n'ụbọchị, na afọ efu ma ọ bụ mgbe ị risịrị nri.N'ime ndị ọrịa na-anabata ngwaahịa a, enwere ike ịbawanye dose ahụ ruo 25 mg (lee [Nnwale ụlọ ọgwụ]).
N'ime ndị ọrịa nwere hypovolemia, a na-atụ aro ka dozie hypovolemia tupu ịmalite iji ngwaahịa a (lee [Akpachara anya]).
Ndị ọrịa nwere nsogbu gbasara akụrụ.
A na-atụ aro ka nyochaa ọrụ gbasara akụrụ tupu ịmalite iji ngwaahịa a, mgbe ahụ, a ga-enyocha ya mgbe niile.
Ndị ọrịa eGFR dị ala karịa 45 ml/min/1.73 m2 ekwesịghị iji ngwaahịa a.
Ndị ọrịa nwere eGFR dị elu karịa 45 ml/min/1.73 m2 adịghị mkpa ịgbanwe dose ahụ.
Ọ bụrụ na eGFR na-aga n'ihu na-agbada karịa 45 ml/min/1.73 m2, a ga-akwụsị ngwaahịa a (lee [Akpachara anya]).
Ndị ọrịa nwere mmebi imeju.
Ndị ọrịa nwere mmebi imeju adịghị mkpa ịgbanwe dose ahụ.Mkpughe nke Enpagliflozin na-abawanye na ndị ọrịa nwere nnukwu mmebi imeju.Ahụmahụ ọgwụgwọ nke ndị ọrịa nwere nnukwu mmebi imeju dị oke, ya mere, a naghị atụ aro ya maka akụkụ a nke ọnụ ọgụgụ mmadụ.
Ọkọlọtọ:ọkọlọtọ ụlọ ọrụ
ịdị ọcha:≥99.0%
Mputa:ọcha na-acha ọcha ntụ ntụ
ngwugwu:25kg / agba
JIN DUN Medical nwereNtozu ISO ma mezuo ụkpụrụ mmepụta GMP, n'ọrụ ụlọ na mba ọzọ ọgwụ synthesis ọkachamara na ọgaranya ahụmahụ na-eduzi ụlọ ọrụ R&D.
TECHNOL OGY URU
● Nnukwu nrụgide catalytic Hydrogenation.Mmeghachi omume Hydrogenolysis nrụgide dị elu.Mmeghachi omume Cryogenic (<-78%C)
●Aromatic Heterocyclic Synthesis
●Mmeghachi omume
● Mkpebi Chiral
●Heck, Suzuki,Negishi,Sonogashira .Mmeghachi omume Gignard
Akụrụngwa
Ụlọ nyocha anyị nwere ngwaọrụ nnwale na nnwale dị iche iche, dị ka: NMR (Bruker 400M), HPLC, Chiral-HPLC, LC-MS, LC-MS/MS (API 4000) , IR, UV, GC, GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Iche Iche Nyocha Calorimeter (DSC), Electron Microscope...
Otu R&D
Jindun Medical nwere otu ndị ọrụ R&D ọkachamara, ma were ọtụtụ ndị ọkachamara n'ime ụlọ na ndị mba ofesi na-eduzi R&D, na-eme ka njikọ anyị dịkwuo mma na nke ọma.
Anyị enyerela aka ọtụtụ ụlọ ọrụ na-emepụta ọgwụ ụlọ, dịkaHansoh, Hengrui na HEC Pharm.N'ebe a, anyị ga-egosi akụkụ nke ha.
Usoro nhazi nke mbụ:
Nọmba ekwentị: 110351-94-5
Nhazi nke abụọ:
Nọmba ekwentị: 144848-24-8
Usoro nke atọ:
Nọmba cas: 200636-54-0
1.Hazie ndị etiti ọhụrụ ma ọ bụ API.Otu dị ka nkesa nke dị n'elu, ndị ahịa nwere ihe achọrọ maka Intermediates ma ọ bụ API, na ha enweghị ike ịchọta ngwaahịa ndị dị mkpa na ahịa, mgbe ahụ anyị nwere ike inye aka hazie.
2.Usoro nkwalite maka ngwaahịa ochie.Ndị otu anyị ga-enyere aka ịkwalite ma melite mmepụta dị otú ahụ nke ụzọ mmeghachi omume ya mere ochie, ọnụ ahịa mmepụta dị elu, na arụmọrụ dị ala.Anyị nwere ike ịnye akwụkwọ zuru oke maka ịnyefe teknụzụ na nkwalite usoro, nyere ndị ahịa aka maka mmepụta nke ọma.
Site na ebumnuche ọgwụ ruo IND, JIN DUN Medical na-enye gịngwọta R&D ahaziri otu nkwụsị.
JIN DUN Medical na-ekwusi ike ịmepụta otu ndị nwere nrọ, na-emepụta ngwaahịa ndị nwere nsọpụrụ, ndị na-akpachapụ anya, siri ike, na-eme ka ọ bụrụ onye mmekọ tụkwasịrị obi na enyi ndị ahịa!
