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5,6,7,7a-tetrahydrothieno(3,2-c) pyridine-2(4h) -otu hydrochloride

5,6,7,7a-tetrahydrothieno(3,2-c)pyridine-2(4h) -otu foto egosipụtara hydrochloride
  • 5,6,7,7a-tetrahydrothieno(3,2-c) pyridine-2(4h) -otu hydrochloride

5,6,7,7a-tetrahydrothieno(3,2-c) pyridine-2(4h) -otu hydrochloride

Nkọwa dị mkpirikpi:

CAS no: 115473-15-9

Njirimara kemịkalụ: Prasugrel Intermediates


Nkọwa ngwaahịa

Mkpado ngwaahịa

Na-eji

5,6,7,7a-tetrahydrothieno (3,2-c) pyridine-2 (4h) - otu hydrochloride na-eji dị ka etiti nke Prasugrel.
Prasugrel bụ thiophenopyridine antiplatelet mepụtara nke Eli Lilly na daiichisankyo, onye na-emepụta ọgwụ na Japan.Ọ bụ precursor ọgwụ.Ọ na-etolite molekul na-arụ ọrụ mgbe metabolism site na cytochrome P450 n'ime imeju ma jikọta ya na onye na-anabata platelet P2Y12 iji mee ihe na-arụsi ọrụ ike megide nchịkọta platelet.Nnyocha ụlọ ọgwụ egosila na dose 60 mg nwere mmetụta anticoagulant ka mma karịa 300 mg ọkọlọtọ dose na 600 mg na-abawanye dose nke clopidogrel, nke nwere ike belata ihe egwu nke nkụchi obi, ọrịa strok na ọnwụ n'ihi ọrịa obi site na 20%, ma nwee mmetụta ngwa ngwa. , mmetụta ọgwụgwọ dị mma, ezigbo mgbochi ọgwụ na bioavailability, na obere nsị.

Ahịrị ngwaahịa agbakwunyere akụrụngwa

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Asambodo

JIN DUN Medical nwereNtozu ISO ma mezuo ụkpụrụ mmepụta GMP, n'ọrụ ụlọ na mba ọzọ ọgwụ synthesis ọkachamara na ọgaranya ahụmahụ na-eduzi ụlọ ọrụ R&D.

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Uru dị na nhazi nhazi ahụike

TECHNOL OGY URU
● Nnukwu nrụgide catalytic Hydrogenation.Mmeghachi omume Hydrogenolysis nrụgide dị elu.Mmeghachi omume Cryogenic (<-78%C)
●Aromatic Heterocyclic Synthesis
●Mmeghachi omume
● Mkpebi Chiral
●Heck, Suzuki,Negishi,Sonogashira .Mmeghachi omume Gignard

JIN DUN R&D

Akụrụngwa

Ụlọ nyocha anyị nwere ngwaọrụ nnwale na nnwale dị iche iche, dị ka: NMR (Bruker 400M), HPLC, Chiral-HPLC, LC-MS, LC-MS/MS (API 4000) , IR, UV, GC, GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Iche Iche Nyocha Calorimeter (DSC), Electron Microscope...

Otu R&D

Jindun Medical nwere otu ndị ọrụ R&D ọkachamara, ma were ọtụtụ ndị ọkachamara n'ime ụlọ na ndị mba ofesi na-eduzi R&D, na-eme ka njikọ anyị dịkwuo mma na nke ọma.

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Ịkekọrịta ikpe

Anyị enyerela aka ọtụtụ ụlọ ọrụ na-emepụta ọgwụ ụlọ, dịkaHansoh, Hengrui na HEC Pharm.N'ebe a, anyị ga-egosi akụkụ nke ha.

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Usoro nhazi nke mbụ:

Nọmba ekwentị: 110351-94-5

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Nhazi nke abụọ:

Nọmba ekwentị: 144848-24-8

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Usoro nke atọ:

Nọmba cas: 200636-54-0

Ụdị imekọ ihe ọnụ

1.Hazie ndị etiti ọhụrụ ma ọ bụ API.Otu dị ka nkesa nke dị n'elu, ndị ahịa nwere ihe achọrọ maka Intermediates ma ọ bụ API, na ha enweghị ike ịchọta ngwaahịa ndị dị mkpa na ahịa, mgbe ahụ anyị nwere ike inye aka hazie.

2.Usoro nkwalite maka ngwaahịa ochie.Ndị otu anyị ga-enyere aka ịkwalite ma melite mmepụta dị otú ahụ nke ụzọ mmeghachi omume ya mere ochie, ọnụ ahịa mmepụta dị elu, na arụmọrụ dị ala.Anyị nwere ike ịnye akwụkwọ zuru oke maka ịnyefe teknụzụ na nkwalite usoro, nyere ndị ahịa aka maka mmepụta nke ọma.

Site na ebumnuche ọgwụ ruo IND, JIN DUN Medical na-enye gịngwọta R&D ahaziri otu nkwụsị.

JIN DUN Medical na-ekwusi ike ịmepụta otu ndị nwere nrọ, na-emepụta ngwaahịa ndị nwere nsọpụrụ, ndị na-akpachapụ anya, siri ike, na-eme ka ọ bụrụ onye mmekọ tụkwasịrị obi na enyi ndị ahịa!

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