• NEBANNER

2-bromo-2- (2-fluorophenyl) -1-cyclopropylethanone

2-bromo-2- (2-fluorophenyl) -1-cyclopropylethanone

Nkọwa dị mkpirikpi:

CAS no: 204205-33-4

Njirimara kemịkalụ: Prasugrel Intermediates


Nkọwa ngwaahịa

Mkpado ngwaahịa

Na-eji

A na-eji 2-bromo-2- (2-fluorophenyl) -1-cyclopropylethanone dị ka etiti nke Prasugrel.
Prasugrel bụ thiophenopyridine antiplatelet mepụtara nke Eli Lilly na daiichisankyo, onye na-emepụta ọgwụ na Japan.Ọ bụ precursor ọgwụ.Ọ na-etolite molekul na-arụ ọrụ mgbe metabolism site na cytochrome P450 n'ime imeju ma jikọta ya na onye na-anabata platelet P2Y12 iji mee ihe na-arụsi ọrụ ike megide nchịkọta platelet.Nnyocha ụlọ ọgwụ egosila na dose 60 mg nwere mmetụta anticoagulant ka mma karịa 300 mg ọkọlọtọ dose na 600 mg na-abawanye dose nke clopidogrel, nke nwere ike belata ihe egwu nke nkụchi obi, ọrịa strok na ọnwụ n'ihi ọrịa obi site na 20%, ma nwee mmetụta ngwa ngwa. , mmetụta ọgwụgwọ dị mma, ezigbo mgbochi ọgwụ na bioavailability, na obere nsị.


  • Nke gara aga:
  • Osote:

  • Dee ozi gị ebe a ziga anyị ya