Cyclopropyl 2-fluorobenzyl ketone

A na-eji Cyclopropyl 2-fluorobenzyl ketone mee ihe dị ka etiti nke Prasugrel.
Prasugrel bụ thiophenopyridine antiplatelet mepụtara nke Eli Lilly na daiichisankyo, onye na-emepụta ọgwụ na Japan.Ọ bụ precursor ọgwụ.Ọ na-etolite molekul na-arụ ọrụ mgbe metabolism site na cytochrome P450 n'ime imeju ma jikọta ya na onye na-anabata platelet P2Y12 iji mee ihe na-arụsi ọrụ ike megide nchịkọta platelet.Nnyocha ụlọ ọgwụ egosila na dose 60 mg nwere mmetụta anticoagulant ka mma karịa 300 mg ọkọlọtọ dose na 600 mg na-abawanye dose nke clopidogrel, nke nwere ike belata ihe egwu nke nkụchi obi, ọrịa strok na ọnwụ n'ihi ọrịa obi site na 20%, ma nwee mmetụta ngwa ngwa. , mmetụta ọgwụgwọ dị mma, ezigbo mgbochi ọgwụ na bioavailability, na obere nsị.